Recent Publications
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Clonal expansion of cytotoxic CD8⁺ T cells in lecanemab-associated ARIA
30 January 2026 Nature Communications Johnson L.A., Saito K., Pallerla A.V., Funnell J.L., Ezzo A.R., Song C.M., Harrison D.A., Norton N.J., Moore L.C., Van Eldik L.J., Fardo D.W., Cooper G.E., Morganti J.M. |
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Tau pathology reprograms glucose metabolism to support cortical hyperexcitability, excitatory/inhibitory imbalance, and sleep loss
25 January 2026 npj Dementia Irmen R.E., Turner S.M., Snipes A.J., Williams H.C., Viswanathan V.G., Sullivan P.G., Lee D.C., Johnson L.A., Macauley S.L. |
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Reply to: a quantitative trait locus for reduced microglial APOE expression associates with reduced cerebral amyloid angiopathy
26 January 2026 Nature Genetics Shade L.M.P., Qi Q., Johnson L.A., Katsumata Y., Ebbert M.T., Nelson P.T., Fardo D.W. |
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Microglia-selective expression of APOE2 improves remyelination even in the presence of CNS APOE4
11 December 2025 Journal of Neuroinflammation Nolt G.L., Golden L.R., Thorpe S.P., Funnell J.L., Stephens I.O., Hernandez G., MacLean S.M., Lucido C.C., Brock C.R., Adreon D.R., Williams H.C., Morganti J.M., Johnson L.A. |
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Acute effects of lactate infusion on metabolism, AD biomarkers, and cognition: The LEAN study
10 December 2025 Alzheimer’s & Dementia Kemna R.E., Kueck P.J., Blankenship A., John C.S., Johnson C.N., Green Z.D., Mayfield H., Yoksh L., Johnson L., Thyfault J.P., Mahnken J.D., Miller B.F., Morris J.K. |
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Knockout of Perilipin-2 in Microglia Alters Lipid Droplet Accumulation and Response to Alzheimer’s Disease Stimuli
12 November 2025 Cells Stephens I.O. and Johnson L.A. |
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APOE-directed therapeutics in Alzheimer's disease
12 November 2025 Journal of Neuroscience Yassine H., Hugo C., O'Donovan B., Stevens I.O., Johnson L.A., Cole G., TCW J., Johansson J., Kisler K., Chiba-Falek O. |
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APOE4 to APOE2 allelic switching in mice improves Alzheimer’s disease-related metabolic signatures, neuropathology and cognition
11 November 2025 Nature Neuroscience Golden L.R., Siano D.S., Stephens I.O., Maclean S.M., Saito K., Nolt G.L., Funnell J.L., Pallerla A.V., Lee S., Smith C., Chen J., Zhu H., Voy C., Whitus C.M., Hernandez G., Farmer B.C., Pandya K., Cowley D.O., Macauley S., Gordon S.M., Morganti J.M., Johnson L.A. |
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APOE4 alters the lipid droplet proteome and modulates droplet dynamics
2 June 2025 Neurobiology of Disease Friday C.M.*, Stephens I.O.*, Smith C.T., Lee S., Satish D., Devanney N.A., Cohen S., Morganti J.M., Gordon S.M., Johnson L.A. |
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ATP-sensitive potassium channels alter glycolytic flux to modulate cortical activity and sleep
18 February 2025 PNAS Constantino N.J., Carroll C.M., Williams H.C., Vekaria H.J., Yuede C.M., Saito K., Sheehan P.W., Snipes J.A., Raichle M.E., Musiek E.S., Sullivan P.G., Morganti J.M., Johnson L.A., Macauley S.L. |